2020年6月29日，国际学术期刊BMJ (影响因子：30.223)发表了我校首席教授李铎和美国、英国、加拿大四位学者的文章：“Health effects of vitamin and mineral supplements（维生素和矿物质补充剂对健康的影响）”，文章的关键信息是：
The manuscript “Health effects of vitamin and mineral supplements” had been published on the BMJ (Impact factor 30.223) by Duo Li and colleagues In the manuscript, it had been discovered that,
1.Randomised trial evidence does not support use of vitamin, mineral, and fish oil supplements to reduce the risk of non-communicable diseases
2.People using supplements tend to be older, female, and have higher education, income, and healthier lifestyles than people who do not use them
3.Use of supplements appreciably reduces the prevalence of inadequate intake for most nutrients but also increases the prevalence of excess intake for some nutrients
4.Further research is needed to assess the long term effects of supplements on the health of the general population and in individuals with specific nutritional needs, including those from low and middle income countries
The prevalence of use has increased for some vitamin and mineral. In the US, most people who use supplement are older adults. More women than men use supplements. Supplement use correlates positively with educational and socioeconomic status. It also clusters with healthy lifestyle factors such as not being a smoker or heavy drinker, not being overweight or obese, and being physically active. Importantly, people who use supplements tend to have a better overall diet quality. Despite the high use of supplements, inadequate intakes of micronutrients are still common in high income countries, where dietary patterns are typically energy rich but nutrient poor. It remains controversial whether supplements are effective in reducing the risk of non-communicable diseases. In contrast to results of observational studies, the accumulated evidence from randomised controlled trials does not support benefits of supplements in reducing risks of cardiovascular disease, cancer, or type 2 diabetes in healthy people with no clinical nutritional deficiencies. Therefore, continuing efforts are warranted to further understand the potentially different roles of nutrients from foods versus supplements in health promotion among a generally healthy population as well as individuals or groups with specific nutritional needs, including those living in low and middle income countries. These efforts, coupled with the integration of new research approaches, such as nutrigenetics and “omics” sciences, will better inform clinical practice and public health policies.
Zhang FF, Barr SI, McNulty H, Li D, Blumberg JB. Health effects of vitamin and mineral supplements. BMJ. 2020;369:m2511. Published 2020 Jun 29. doi:10.1136/bmj.m2511